Effect of Mesenchymal Stem Cells on the cerebral microvascularisation in a rat model of stroke: MRI study
نویسندگان
چکیده
A. MOISAN, E. GRILLON, E. L. BARBIER, F. DE FRAIPONT, C. REMY, M-J. RICHARD, and O. DETANTE INSERM U836 / Joseph Fourier University (Functional and Metabolic Imaging), Grenoble Institute of Neurosciences (GIN), Grenoble, France, Metropolitan, INSERM U823 / Joseph Fourier University, Albert Bonniot Institute, Grenoble, France, Metropolitan, Cell and Tissue Therapy Unit, University Hospital, Grenoble, France, Metropolitan, Stroke Unit, Department of Neurology, University Hospital, Grenoble, France, Metropolitan
منابع مشابه
Effect of Human Umbilical Cord Mesenchymal Stem Cells Transplantation on Nerve Fibers of A Rat Model of Endometriosis
Background Endometriosis is a common, benign, oestrogen-dependent, chronic gynaecological disorder associated with pelvic pain and infertility. Some researchers have identified nerve fibers in endometriotic lesions in women with endometriosis. Mesenchymal stem cells (MSCs) have attracted interest for their possible use for both cell and gene therapies because of their capacity for self-renewal ...
متن کاملPotential Therapeutic Effect of TLR4-Primed Mesenchymal Stem Cells in Lessening Kidney Damages in Rat Model of Diabetic Nephropathy
Background and Aims: Substantial damage to the kidney tissue and diabetic nephropathy (DN) can be caused by chronic hyperglycemic conditions and exposure to a high level of blood glucose. In the current study, we explored the capability of adipose-derived mesenchymal stem cells (ADSCs) and Toll-like receptor-4-primed mesenchymal stem cells (TLR4-primed MSCs) on kidney regeneration, resolution ...
متن کاملEffect of Lithium Chloride on Proliferation and Bone Differentiation of Rat Marrow-Derived Mesenchymal Stem Cells in Culture
Objective(s) It is believed that the mesenchymal stem cell (MSC) differentiation and proliferation are the results of activation of wnt signaling pathway. On the other hand, lithium chloride is reported to be able to activate this pathway. The objective of this study was to investigate the effect of lithium on in vitro proliferation and bone differentiation of marrow-derived MSC. Materials and ...
متن کاملOsteogenic Differentiation of Mesenchymal Stem Cells Via Osteoblast- Imprinted Substrate: In Vitro and In Vivo Evaluation in Rat Model
BACKGROUND: Stem cells have great effects in clinical cell-based therapy. Accordingly, controlling the behavior and directing the fate of stem cells cultured in the laboratory is an important issue. OBJECTIVES: The aim of this study was to evaluate osteogenic properties of adipose derived mesenchymal stem cells (ADSCs) which differentiated toward osteogenic linage by osteoblast-imprinted substr...
متن کاملMesenchymal stem cells that located in the electromagnetic fields improves rat model of Parkinson's disease
Objective(s): The main characteristic of mesenchymal stem cells (MSCs) is their ability to produce other cell types. Electromagnetic field (EMF) stimulates differentiation of MSCs into other cells. In this study, we investigated whether EMF can effect on the differentiation of MSCs into dopaminergic (DA) neurons. Materials and Methods: An EMF with a frequency of 50 Hz and two intensities of 40 ...
متن کامل